Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition
نویسندگان
چکیده
منابع مشابه
Treatment-resistant Depression: Definition and Epidemiology
Treatment-resistant depression (TRD) is a prevalent, disabling, and costly condition affecting 1%–4% of the U.S. population. Current approaches to managing TRD include medication augmentation (with lithium, thyroid hormone, buspirone, atypical antipsychotics, or various antidepressant medications), psychotherapy, and ECT. Advances in understanding the neurobiology of mood regulation and depress...
متن کاملBipolar mood disorder and treatment-resistant depression
Two lines of evidence point to the relationship between bipolar mood disorder and treatment-resistant depression. First, the frequency of suboptimal response to antidepressant drugs is significantly higher in bipolar than in unipolar mood disorder. Secondly, the first and the second generation mood stabilizing drugs are efficacious for augmentation of antidepressants in treatmentresistant depre...
متن کاملTreatment-Resistant Bipolar Disorder
Treatment resistance is extremely common. Even under optimal maintenance conditions, almost half of bipolar patients with symptom remission will have a recurrence in 2 years under standard care (including medication combinations).2 Optimizing phase-specific evidence-based treatments is crucial. This may include raising the dosage of an initial treatment according to response unless limited by a...
متن کاملTreatment-Resistant Bipolar Disorder
Treatment resistance is extremely common. Even under optimal maintenance conditions, almost half of bipolar patients with symptom remission will have a recurrence in 2 years under standard care (including medication combinations).2 Optimizing phase-specific evidence-based treatments is crucial. This may include raising the dosage of an initial treatment according to response unless limited by a...
متن کاملWhen electroconvulsive therapy fails: cognitive– behavioral therapy in treatment-resistant bipolar depression. A case report
Discussion: To date there is a lack of consensus on either the diagnostic criteria of TRBD or evidence-based guidelines for the treatment of TRBD. Adjunctive modafinil, pramipexole, tranylcypromine and vagus nerve stimulation have been tried but the response rate is variable. Family-focused treatment, group psychoeducation and interpersonal and social rhythm therapy have been tried in bipolar d...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2018
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.2018.257